Integrated Multi-omics Analysis of Hub Genes and miRNA Interactions in Hypertrophic Cardiomyopathy

Our findings suggest that IREB2, PTPN11, IQGAP1, PGM2, DIS3, and GFPT1 hub genes and their associated regulatory pathways may serve as biomarkers and therapeutic targets for HCM, potentially improving diagnosis and treatment strategies.

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Publication Details

Journal
Current Genomics
Published
2025-05-05
DOI
https://doi.org/10.2174/0113892029363785250311084956
Citations
2
Primary Topic
Cardiomyopathy and Myosin Studies
Type
article
Field-Weighted Citation Impact
2.78
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article

Integrated Multi-omics Analysis of Hub Genes and miRNA Interactions in Hypertrophic Cardiomyopathy

Kongjie Lu, Lang Deng, Huanhuan Hu, Ziheng Yu et al.
2 citations
Current Genomics
Cardiomyopathy and Myosin Studies
2.78
article

Integrated Multi-omics Analysis of Hub Genes and miRNA Interactions in Hypertrophic Cardiomyopathy

Kongjie Lu, Lang Deng, Huanhuan Hu, Ziheng Yu, Hui Hu
article en
2 citations

Abstract

Our findings suggest that IREB2, PTPN11, IQGAP1, PGM2, DIS3, and GFPT1 hub genes and their associated regulatory pathways may serve as biomarkers and therapeutic targets for HCM, potentially improving diagnosis and treatment strategies.

Current GenomicsVol. 26(5)
Zhejiang Chinese Medical University (CN), Huzhou Normal University (CN), Huzhou Central Hospital (CN)
Openalex Percentile: Top 10%
Cardiomyopathy and Myosin Studies
2.78
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