To determine the role of TRIT1 in the diagnosis, prognosis and immunoinvasion of liver hepatocellular carcinoma
This study provides the first evidence that the presence of TRIT1 can serve as a reliable marker for diagnosis and prognostication of hepatocellular carcinoma. Moreover, TRIT1 emerges as a critical indicator of the potential for cancer infiltration and invasion of the immune system, holding significant implications for the development of targeted therapies for hepatocellular carcinoma.
Authors
- Tingting Zhou (ORCID: https://orcid.org/0000-0001-8084-178X)
- Yujuan Tang
- Xiaona Pan (ORCID: https://orcid.org/0000-0002-6037-3680)
- Xinyu Niu (ORCID: https://orcid.org/0000-0001-8026-701X)
- Chao Xuan (ORCID: https://orcid.org/0000-0001-8273-0178)
- Yuan Yuan (ORCID: https://orcid.org/0000-0002-4041-8765)
- Yaqi Song (ORCID: https://orcid.org/0000-0001-8236-2643)
- Jingqiu Chen
- Qingwu Tian
- Guifang He
Institutions
- Qingdao University (CN)
- Hubei Provincial Hospital of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-05
- DOI
- https://doi.org/10.3389/fimmu.2025.1563442
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province