Targeting JAK‐1 in Disseminated Cutaneous Lichen Planus

ABSTRACT We report the case of a 63‐year‐old woman with an exuberant and recalcitrant clinical presentation of LP who had an excellent response to 200 mg/day abrocitinib, a JAK‐1 inhibitor, after failure to other commonly used therapies. The efficacy of JAK inhibitors in lichen planus is supported by small case series and isolated case reports. Further studies are necessary to confirm their full potential.

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Publication Details

Journal
JEADV Clinical Practice
Published
2025-05-04
DOI
https://doi.org/10.1002/jvc2.70054
Citations
1
Primary Topic
Oral Health Pathology and Treatment
Type
article
Field-Weighted Citation Impact
1.47
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article

Targeting JAK‐1 in Disseminated Cutaneous Lichen Planus

Lara de Melo Siems, Artur Antônio Duarte, Dimitri Luz, Flávio Henrique Ferreira Barbosa
1 citations
JEADV Clinical Practice
Oral Health Pathology and Treatment
1.47
article

Targeting JAK‐1 in Disseminated Cutaneous Lichen Planus

Lara de Melo Siems, Artur Antônio Duarte, Dimitri Luz, Flávio Henrique Ferreira Barbosa
article en
1 citations

Abstract

ABSTRACT We report the case of a 63‐year‐old woman with an exuberant and recalcitrant clinical presentation of LP who had an excellent response to 200 mg/day abrocitinib, a JAK‐1 inhibitor, after failure to other commonly used therapies. The efficacy of JAK inhibitors in lichen planus is supported by small case series and isolated case reports. Further studies are necessary to confirm their full potential.

JEADV Clinical PracticeVol. 4(4)
Universidade de Santo Amaro (BR)
Openalex Percentile: Top 20%
Oral Health Pathology and Treatment
1.47
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