Efficacy and safety of low-dose X-rays based intraoperative radiotherapy for high-grade gliomas: a single-center retrospective study
Low-dose X-rays based IORT at doses of 10-12 Gy is generally safe for HGGs. Future prospective large-scale studies are needed to further evaluate the efficacy and safety of IORT with escalating doses. Even with the use of IORT, post-operative radiotherapy is essential for improving clinical outcomes of HGGs. This study provides clinical data on IORT for HGGs, which may represent a promising therapeutic approach for managing this disease.
Authors
- Ying Yan (ORCID: https://orcid.org/0000-0002-3546-3991)
- Peng Cao (ORCID: https://orcid.org/0000-0002-2044-3074)
- Jiajie He (ORCID: https://orcid.org/0000-0002-1532-0870)
- Shun Gong (ORCID: https://orcid.org/0000-0003-3338-7996)
- Minggen Zhou (ORCID: https://orcid.org/0000-0002-4574-9299)
- Jianan Li (ORCID: https://orcid.org/0000-0002-0894-4060)
- Rui Li (ORCID: https://orcid.org/0000-0001-7857-9735)
- Ying Xu (ORCID: https://orcid.org/0000-0003-1452-8423)
- Yang Bai (ORCID: https://orcid.org/0000-0001-7466-4393)
- Zhongcheng Wen
- F. Li
Institutions
- Dalian Medical University (CN)
- General Hospital of Shenyang Military Region (CN)
- Jinzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-05-05
- DOI
- https://doi.org/10.3389/fonc.2025.1548276
- Citations
- 1
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.63