Chromosome-scale scaffolds of the fungus gnat genome reveal multi-Mb-scale chromosome-folding interactions, centromeric enrichments of retrotransposons, and candidate telomere sequences

The chromosome scaffolds were shown to be of exceptional quality, including loci harboring horizontally-transferred genes. Repeat analyses demonstrate family-specific biases and telomere repeat candidates. Hi-C analyses revealed the sequences of ultra-long-range interactions on the X chromosome. The chromosome-scale scaffolds pave the way for further studies of the unusual chromosome movements in Bradysia coprophila.

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Publication Details

Journal
BMC Genomics
Published
2025-05-05
DOI
https://doi.org/10.1186/s12864-025-11573-2
Citations
2
Primary Topic
Chromosomal and Genetic Variations
Type
article
Field-Weighted Citation Impact
3.50

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article

Chromosome-scale scaffolds of the fungus gnat genome reveal multi-Mb-scale chromosome-folding interactions, centromeric enrichments of retrotransposons, and candidate telomere sequences

Allan C. Spradling, John Urban, Susan A. Gerbi
2 citations
BMC Genomics
Chromosomal and Genetic Variations
3.50
article

Chromosome-scale scaffolds of the fungus gnat genome reveal multi-Mb-scale chromosome-folding interactions, centromeric enrichments of retrotransposons, and candidate telomere sequences

Allan C. Spradling, John Urban, Susan A. Gerbi
article en
2 citations

Abstract

The chromosome scaffolds were shown to be of exceptional quality, including loci harboring horizontally-transferred genes. Repeat analyses demonstrate family-specific biases and telomere repeat candidates. Hi-C analyses revealed the sequences of ultra-long-range interactions on the X chromosome. The chromosome-scale scaffolds pave the way for further studies of the unusual chromosome movements in Bradysia coprophila.

BMC GenomicsVol. 26(1)
Howard Hughes Medical Institute (US), Carnegie Institution for Science (US), Brown University (US), Department of Embryology (US)
Howard Hughes Medical Institute, National Institutes of Health
Life in Land
Openalex Percentile: Top 9%
Chromosomal and Genetic Variations
3.50
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