Acute Response of Hepatocyte MRP2 Internalization as an Indicator of Ischemia-reperfusion Injury in Liver Transplantation

MRP2 is a putative biomarker for the assessment of hepatic ischemia-reperfusion injury. The biliary excretion kinetics of sodium fluorescein reflects MRP2-mediated transport activity, providing a novel diagnostic method for predicting liver graft viability after LT.

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Publication Details

Journal
Transplantation
Published
2025-05-05
DOI
https://doi.org/10.1097/tp.0000000000005418
Citations
1
Primary Topic
Organ Transplantation Techniques and Outcomes
Type
article
Field-Weighted Citation Impact
2.01
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article

Acute Response of Hepatocyte MRP2 Internalization as an Indicator of Ischemia-reperfusion Injury in Liver Transplantation

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1 citations
Transplantation
Organ Transplantation Techniques and Outcomes
2.01
article

Acute Response of Hepatocyte MRP2 Internalization as an Indicator of Ischemia-reperfusion Injury in Liver Transplantation

Said H. Audi, Christopher Monti, Johnny C. Hong, Alice Lee, Whayoung Lee, Ranjan K. Dash, Amit Joshi, Calvin Eriksen, Joohyun Kim, Suresh N. Kumar, Seung-Keun Hong
article en
1 citations

Abstract

MRP2 is a putative biomarker for the assessment of hepatic ischemia-reperfusion injury. The biliary excretion kinetics of sodium fluorescein reflects MRP2-mediated transport activity, providing a novel diagnostic method for predicting liver graft viability after LT.

TransplantationVol. 109(9)
Marquette University (US), Medical College of Wisconsin (US)
Good health and well-being
Openalex Percentile: Top 16%
Organ Transplantation Techniques and Outcomes
2.01
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