ANALYSIS OF HOSPITAL COMPLICATIONS OF USING XENOBIOPROSTHESIS “KEMANGIOPROSTHESIS” IN COMPARISON WITH SYNTHETIC PROSTHESES FOR THE FORMATION OF PERMANENT VASCULAR ACCESS IN PATIENTS UNDERGOING CHRONIC HEMODIALYSIS

Highlights • The KemAngioprosthesis xenobioprosthesis, in comparison with the synthetic ePTFE prosthesis, demonstrates satisfactory results in the formation of permanent vascular access for chronic hemodialysis, comparable with literature data.• The KemAngioprosthesis xenobioprosthesis may be an alternative to the synthetic ePTFE prosthesis in clinical practice while providing vascular access for long-term renal replacement therapy. Abstract Aim . Comparative analysis of hospital complications of the use of xenobioprosthesis “KemAngioprosthesis” for the formation of permanent vascular access in comparison with prostheses made of synthetic material ePTFE (Venaflo II). Methods . This study will present data from two centers and analyze hospital complications. Eighty-two patients were included in the retrospective two-center study, which were divided into two groups depending on the type of prosthesis used. Fifty operations using a biological prosthesis “KemAngioprosthesis”. And thirty-two cases of surgical interventions using a synthetic prosthesis made of ePTFE (Venaflo II). Results . In the KemAngioprosthesis and Venaflo II groups, the following were registered: Still syndrome 2( 4%) and 2 (6%), (p = 0.641), prosthetic thrombosis 2 (4%) and 2 (6%), (p = 0.641), bleeding 1 (2%) and 1 (3%), (p = 1.000), hematomas 3 (8%) and 3 (10%), (p = 0.674). The combined endpoint is 7 (14%) and 7 (21%), respectively (p = 0.381). Conclusion . Based on the comparative analysis conducted with a comparison of the hospital results of the use of the Xenobioprosthesis “KemAngioprosthesis” and a synthetic prosthesis made of ePTFE (Venaflo II), it is possible to conclude about the comparable frequency and structure of the main adverse events. Both types of prosthesis in the formation of permanent vascular access for chronic hemodialysis demonstrate satisfactory results comparable with the literature data. This allows us to conclude that in clinical practice, when providing vascular access for long-term renal replacement therapy, the xenobioprosthesis “KemAngioprosthesis” can be an alternative to a synthetic prosthesis made of ePTFE