Incident HFpEF and time-dependent changes in markers of LVDD severity in women and men with preclinical LVDD
Our study demonstrates that only a small proportion of women and men with preclinical LVDD develop incident HF over a roughly 5-year follow-up period. High blood pressure and decreased kidney function were associated with higher levels of NT-proBNP. This highlights the need to further explore cardiorenal protection as a method to prevent HFpEF.
Authors
- Elisa Dal Canto (ORCID: https://orcid.org/0000-0001-8999-9946)
- Anne Margje Lisa Naomi van Ommen (ORCID: https://orcid.org/0000-0003-1249-0767)
- M. Louis Handoko (ORCID: https://orcid.org/0000-0002-8942-7865)
- Frans Hendrik Rutten (ORCID: https://orcid.org/0000-0002-5052-7332)
- N. Charlotte Onland‐Moret (ORCID: https://orcid.org/0000-0002-2360-913X)
- Maarten J. Cramer (ORCID: https://orcid.org/0000-0002-6041-6759)
- Karim Taha (ORCID: https://orcid.org/0000-0001-6508-5461)
- Ernest Diez Benavente (ORCID: https://orcid.org/0000-0002-4313-4290)
- Roxana Menken (ORCID: https://orcid.org/0000-0002-6314-9238)
- Marianne Christina Verhaar (ORCID: https://orcid.org/0000-0002-3276-6428)
- Dirk Jan Duncker (ORCID: https://orcid.org/0000-0003-2836-2241)
- Arco J. Teske (ORCID: https://orcid.org/0000-0001-5305-1619)
- Hester M. den Ruijter (ORCID: https://orcid.org/0000-0001-9762-014X)
Institutions
- Utrecht University (NL)
- Erasmus MC (NL)
- University Medical Center Utrecht (NL)
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- Open Heart
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1136/openhrt-2024-003105
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Dutch Cardiovascular Alliance