Exploring the Bioactive Constituents and Therapeutic Mechanisms of Sanhuang Xiexin Decoction in Hypercholesterolemia Treatment Using UHPLC‐Q‐Orbitrap‐MS/MS Integrated With Metabolomics and Network Pharmacology
SHD exerts its therapeutic effects on HC through multiple targets and multiple mechanisms. This study lays the groundwork for the clinical application of SHD in the treatment of HC and paves the way for further exploration of its underlying mechanisms.
Authors
- Junli Hong (ORCID: https://orcid.org/0009-0005-7384-2692)
- Lin Wang (ORCID: https://orcid.org/0000-0002-6677-7061)
- Jun Zhang (ORCID: https://orcid.org/0000-0002-5843-8705)
- Yatong Zhu
- Xinlei Yang (ORCID: https://orcid.org/0000-0003-0462-7532)
- Furong Wang (ORCID: https://orcid.org/0000-0002-1799-6735)
- Mengting Zhao (ORCID: https://orcid.org/0000-0002-1782-0756)
Institutions
- Yantai University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Rapid Communications in Mass Spectrometry
- Published
- 2025-05-04
- DOI
- https://doi.org/10.1002/rcm.10035
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00