Attenuating Mutations in Usutu Virus: Towards Understanding Orthoflavivirus Virulence Determinants and Live Attenuated Vaccine Design
In addition to improving our understanding of USUV virulence determinants, these results add to a growing body of literature highlighting the most promising mechanisms to target for the design of safe live attenuated vaccines against emerging orthoflaviviruses.
Authors
- Johanna M. Duyvestyn (ORCID: https://orcid.org/0000-0001-9163-2318)
- Marjolein Kikkert (ORCID: https://orcid.org/0000-0002-5779-7386)
- Martijn J. van Hemert (ORCID: https://orcid.org/0000-0002-2617-9243)
- Tessa Nelemans (ORCID: https://orcid.org/0000-0003-3118-3949)
- Ali Taş (ORCID: https://orcid.org/0009-0001-1497-766X)
- Peter J. Bredenbeek
- Marie J. Gruters
Institutions
- Leiden University Medical Center (NL)
Publication Details
- Journal
- Vaccines
- Published
- 2025-05-03
- DOI
- https://doi.org/10.3390/vaccines13050495
- Citations
- 1
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Leids Universitair Medisch Centrum