Patterns of Recurrence After Postoperative Stereotactic Radiotherapy for Brain Metastases

This study examined patterns of recurrence after postoperative radiotherapy and its implications for radiation dose, radiation field size, and treatment sequence. Local control was high after total resection. Radiation field size appeared adequate given the low incidence of marginal recurrences. Patients with cerebellar metastases showed an increased risk of LMD, underscoring the need for preventive measures, particularly preoperative SRT.

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Publication Details

Journal
Cancers
Published
2025-05-03
DOI
https://doi.org/10.3390/cancers17091557
Citations
1
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
1.52
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article

Patterns of Recurrence After Postoperative Stereotactic Radiotherapy for Brain Metastases

Anna L. Petoukhova, Thijs van der Vaart, Johan A F Koekkoek, Rob J.A. Nabuurs et al.
1 citations
Cancers
Brain Metastases and Treatment
1.52
article

Patterns of Recurrence After Postoperative Stereotactic Radiotherapy for Brain Metastases

Anna L. Petoukhova, Thijs van der Vaart, Johan A F Koekkoek, Rob J.A. Nabuurs, Lisette M. Wiltink, M. Mast, Jeroen A. Crouzen, Noëlle C.M.G. van der Voort van Zyp, Mandy Kiderlen, Rishi Nandoe Tewarie, Marike L. D. Broekman, Melissa Kerkhof, Jaap Zindler, Maaike J. Vos, Rogier E. Hagenbeek, Martijn Hakstege, Elise E. M. W. van Schaik, Fatih M. Yildirim
article en
1 citations

Abstract

This study examined patterns of recurrence after postoperative radiotherapy and its implications for radiation dose, radiation field size, and treatment sequence. Local control was high after total resection. Radiation field size appeared adequate given the low incidence of marginal recurrences. Patients with cerebellar metastases showed an increased risk of LMD, underscoring the need for preventive measures, particularly preoperative SRT.

CancersVol. 17(9)
Leiden University Medical Center (NL), The Netherlands Cancer Institute (NL), Medisch Centrum Haaglanden (NL), Huisman (Netherlands) (NL)
Good health and well-being
Openalex Percentile: Top 19%
Brain Metastases and Treatment
1.52
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Patterns of Recurrence After Postoperative Stereotactic Radiotherapy for Brain Metastases — Anna L. Petoukhova, Thijs van der Vaart, et al. · Cancers (2025) | TGRS Research Map | TGRS