Muscle weakness but also contractures contribute to the progressive gait pathology in children with Duchenne muscular dystrophy: a simulation study
Predictive simulations have the potential to elucidate causal relationships between muscle impairments and gait deviations in boys with DMD. In the future, they could be used to design targeted interventions (e.g. stretching, assistive devices) to prolong ambulation.
Authors
- Lars D’Hondt (ORCID: https://orcid.org/0000-0002-2971-7297)
- Kaat Desloovere (ORCID: https://orcid.org/0000-0002-8507-5276)
- Ines Vandekerckhove (ORCID: https://orcid.org/0000-0002-6023-3004)
- Liesbeth De Waele (ORCID: https://orcid.org/0000-0001-7126-575X)
- Nathalie Goemans (ORCID: https://orcid.org/0000-0002-5157-7155)
- Friedl De Groote (ORCID: https://orcid.org/0000-0002-4255-8673)
- Anja Van Campenhout (ORCID: https://orcid.org/0000-0002-8158-5535)
- M. van den Hauwe
- Dhruv Gupta (ORCID: https://orcid.org/0000-0002-7561-2007)
- Bram Van Den Bosch (ORCID: https://orcid.org/0000-0002-5099-6331)
Institutions
- KU Leuven (BE)
Publication Details
- Journal
- Journal of NeuroEngineering and Rehabilitation
- Published
- 2025-05-04
- DOI
- https://doi.org/10.1186/s12984-025-01631-x
- Citations
- 1
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Fonds Wetenschappelijk Onderzoek
- Duchenne Parent Project