Investigation of Anti-Cancerous Effects of L. casei –ATCC-393 and L. rhamnosus-GG on Apoptosis and Cell Cycle of B- CPAP Thyroid Cancer Cell line in Comparison to Fibroblast Cell Line
The findings indicated a notable change in the expression of genes associated with apoptosis and modifications in the cell cycle. This implies that probiotics may enhance the efficacy of chemotherapy in treating thyroid cancer. In particular, <i>L. rhamnosus</i> and <i>L. casei</i> may play a beneficial role in the therapeutic process. Further research is required to investigate the direct impact of probiotics on thyroid function.
Authors
- Maryam Darvish (ORCID: https://orcid.org/0000-0002-1030-496X)
- Maryam Honardoost (ORCID: https://orcid.org/0000-0002-1285-8456)
- Hamed Haddad Kashani (ORCID: https://orcid.org/0000-0003-2606-2886)
- Sara Cheraghi (ORCID: https://orcid.org/0000-0003-2490-2757)
- Solat Eslami (ORCID: https://orcid.org/0000-0002-4205-7780)
- Mohammad E. Khamseh (ORCID: https://orcid.org/0000-0003-4313-8440)
- Fatemeh Soleimanifar (ORCID: https://orcid.org/0000-0002-8096-9924)
Institutions
- Arak University of Medical Sciences (IR)
- Iran University of Medical Sciences (IR)
- Kashan University of Medical Sciences (IR)
- Jahrom University of Medical Sciences (IR)
- Alborz University of Medical Sciences (IR)
Publication Details
- Journal
- Avicenna Journal of Medical Biotechnology
- Published
- 2025-05-04
- DOI
- https://doi.org/10.18502/ajmb.v17i2.18561
- Citations
- 1
- Primary Topic
- Nutrition, Genetics, and Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.82