Identification and validation of susceptibility modules and hub genes of adrenocortical carcinoma through WGCNA and machine learning
This study sheds light on the mechanisms underlying ACC progression and highlights potential therapeutic targets. By identifying specific immune cell subtypes associated with ACC, the findings may aid in developing immune modulation therapies aimed at preventing or treating ACC.
Authors
- Xinbao Wang
- Ran Chen (ORCID: https://orcid.org/0000-0002-0296-1724)
- Guoyong Yu (ORCID: https://orcid.org/0000-0001-6314-3963)
- Yaoming Yang
- Shihua Zhao (ORCID: https://orcid.org/0000-0003-1339-7476)
- L C Wu
Institutions
- Beijing University of Chinese Medicine (CN)
- Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-05-03
- DOI
- https://doi.org/10.1007/s12672-025-02396-4
- Citations
- 5
- Primary Topic
- Adrenal and Paraganglionic Tumors
- Type
- article
- Field-Weighted Citation Impact
- 10.03