The REFRACT trial: implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial

Authors

Charlotte Gaskell (ORCID: https://orcid.org/0000-0002-6382-2277)
Kim Linton (ORCID: https://orcid.org/0000-0002-3294-1548)
Aimee Jackson (ORCID: https://orcid.org/0000-0002-9324-9635)
Mark Bishton (ORCID: https://orcid.org/0000-0001-6058-1036)
Tania Seale
Graham McIlroy (ORCID: https://orcid.org/0000-0002-4731-1784)
Siân Lax (ORCID: https://orcid.org/0000-0002-0248-8973)
Malcolm Rhodes
Rebecca Collings
Louise Hopkins
Sonia Fox

Institutions

Nottingham University Hospitals NHS Trust (GB)
University of Nottingham (GB)
University of Manchester (GB)
Cancer Research UK Manchester Institute (GB)
The Christie NHS Foundation Trust (GB)
Cancer Research UK Clinical Trials Unit (GB)
Patient Advocate Foundation (US)
University of Birmingham (GB)

Publication Details

Journal: BMC Medical Research Methodology
Published: 2025-05-03
DOI: https://doi.org/10.1186/s12874-025-02575-5
Primary Topic: Lymphoma Diagnosis and Treatment
Type: article
Field-Weighted Citation Impact: 0.00

Funders

Cancer Research UK

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article

The REFRACT trial: implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial

Charlotte Gaskell, Kim Linton, Aimee Jackson, Mark Bishton et al.

May 3, 2025

BMC Medical Research Methodology

Lymphoma Diagnosis and Treatment

article

The REFRACT trial: implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial

Charlotte Gaskell, Kim Linton, Aimee Jackson, Mark Bishton, Tania Seale, Graham McIlroy, Siân Lax, Malcolm Rhodes, Rebecca Collings, Louise Hopkins, Sonia Fox

May 3, 2025article en

Abstract

No abstract available for this paper.

BMC Medical Research MethodologyVol. 25(1)

Nottingham University Hospitals NHS Trust (GB), University of Nottingham (GB), University of Manchester (GB), Cancer Research UK Manchester Institute (GB), The Christie NHS Foundation Trust (GB), Cancer Research UK Clinical Trials Unit (GB), Patient Advocate Foundation (US), University of Birmingham (GB)

Cancer Research UK

Good health and well-being

Openalex Percentile: Top 86%

Lymphoma Diagnosis and Treatment

DOI Open Access PDF OpenAlex

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The REFRACT trial: implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial — Charlotte Gaskell, Kim Linton, et al. · BMC Medical Research Methodology (2025) | TGRS Research Map | TGRS