Multi-group global tests for restricted mean survival time and restricted mean time lost: a variable transformation approach
The proposed transformation-based global tests offer researchers a flexible, assumption-free tool to compare treatment effects across multiple groups with enhanced reliability and interpretability. Additionally, an R package "compRM" was developed to implement the proposed methods.
Authors
- Shuyu Chen (ORCID: https://orcid.org/0000-0001-5044-4281)
- Chengfeng Zhang (ORCID: https://orcid.org/0000-0002-1302-5667)
- Xin Zhou (ORCID: https://orcid.org/0000-0002-7726-7809)
- Zheng Chen (ORCID: https://orcid.org/0000-0003-3201-2666)
- Mengyao Wang (ORCID: https://orcid.org/0009-0003-3810-8164)
- Wenbin Zhang (ORCID: https://orcid.org/0000-0002-9270-6005)
Institutions
- Southern Medical University (CN)
Publication Details
- Journal
- BMC Medical Research Methodology
- Published
- 2025-05-03
- DOI
- https://doi.org/10.1186/s12874-025-02563-9
- Primary Topic
- Statistical Methods in Clinical Trials
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province