Differences of clinical features, prognosis and genetic mutations in Chinese patients with malignant melanoma and additional primary tumours
The frequency of MM and additional primary tumours is about 5% in Chinese populations. Patients with melanoma diagnosed first have longer melanoma survival. Digestive system tumours were the most concomitant; a digestive examination is advisable, especially for those with an expected overall survival (OS) greater than 10 months. Meanwhile, patient's family cancer history should be followed up in detail, along with completion of germline P/LP mutation and somatic mutation testing, all of which may provide valuable support for further treatment.
Authors
- Yingqian Zhang (ORCID: https://orcid.org/0000-0002-1208-6070)
- Xuan Gao (ORCID: https://orcid.org/0000-0002-7045-9656)
- Bin Lan
- Yu Chen (ORCID: https://orcid.org/0000-0003-4293-1324)
- Zelong Xu
- Huishan Zhang (ORCID: https://orcid.org/0000-0001-5324-9959)
- Yu-Fang Huang (ORCID: https://orcid.org/0000-0002-3832-1294)
- Yanping Chen (ORCID: https://orcid.org/0000-0002-0000-2079)
- Xuefeng Wang (ORCID: https://orcid.org/0000-0002-5980-6530)
- Jing Lin (ORCID: https://orcid.org/0000-0002-9025-1721)
- Zhongqiao Lin (ORCID: https://orcid.org/0000-0002-5539-1526)
- Li Zhu (ORCID: https://orcid.org/0009-0000-3598-9216)
Institutions
- Fujian Medical University (CN)
- Fujian Provincial Cancer Hospital (CN)
- Center for Cancer Research (US)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-05-03
- DOI
- https://doi.org/10.1080/07853890.2025.2493769
- Citations
- 1
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Natural Science Foundation of Fujian Province