Epicardial Adipose Tissue and Heterogeneity Parameters Combined with Inflammatory Cells to Predict the Value of Heart Failure with Preserved Ejection Fraction Patients Post Myocardial Infarction

In patients with chronic MI, normal LVEF, and no prior PCI, the occurrence of HFpEF is not correlated with infarct volume; however, BMI, diabetes, monocyte, LV EAT, and EAT entropy are independent risk factors for HFpEF with significant predictive value, with the highest predictive efficacy observed monocyte and when combining EAT entropy and LV EAT. Additionally, both overall and local EAT volumes exhibit a moderate positive correlation with leukocytes,monocytes and inflammatory markers, and were also positively correlated with diastolic dysfunction. This suggests that, in clinical practice, beyond traditional indicators, there should be an increased focus on EAT heterogeneity and perivascular EAT in MI patients with normal LVEF who have not undergone PCI to to reduce the incidence of HFpEF.

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Publication Details

Journal
Cardiovascular Diabetology
Published
2025-05-03
DOI
https://doi.org/10.1186/s12933-025-02720-w
Citations
5
Primary Topic
Cardiovascular Disease and Adiposity
Type
article
Field-Weighted Citation Impact
6.94

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article

Epicardial Adipose Tissue and Heterogeneity Parameters Combined with Inflammatory Cells to Predict the Value of Heart Failure with Preserved Ejection Fraction Patients Post Myocardial Infarction

Xiaoying Zhao, Mingtian Chen, Lu-jing Wang, Peng Liu et al.
5 citations
Cardiovascular Diabetology
Cardiovascular Disease and Adiposity
6.94
article

Epicardial Adipose Tissue and Heterogeneity Parameters Combined with Inflammatory Cells to Predict the Value of Heart Failure with Preserved Ejection Fraction Patients Post Myocardial Infarction

Xiaoying Zhao, Mingtian Chen, Lu-jing Wang, Peng Liu, Xinxiang Zhao, Siwen Chen, Yujiao Song, Ting Ning
article en
5 citations

Abstract

In patients with chronic MI, normal LVEF, and no prior PCI, the occurrence of HFpEF is not correlated with infarct volume; however, BMI, diabetes, monocyte, LV EAT, and EAT entropy are independent risk factors for HFpEF with significant predictive value, with the highest predictive efficacy observed monocyte and when combining EAT entropy and LV EAT. Additionally, both overall and local EAT volumes exhibit a moderate positive correlation with leukocytes,monocytes and inflammatory markers, and were also positively correlated with diastolic dysfunction. This suggests that, in clinical practice, beyond traditional indicators, there should be an increased focus on EAT heterogeneity and perivascular EAT in MI patients with normal LVEF who have not undergone PCI to to reduce the incidence of HFpEF.

Cardiovascular DiabetologyVol. 24(1)
Kunming Medical University (CN)
Kunming Medical University
Good health and well-being
Openalex Percentile: Top 3%
Cardiovascular Disease and Adiposity
6.94
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Epicardial Adipose Tissue and Heterogeneity Parameters Combined with Inflammatory Cells to Predict the Value of Heart Failure with Preserved Ejection Fraction Patients Post Myocardial Infarction — Xiaoying Zhao, Mingtian Chen, et al. · Cardiovascular Diabetology (2025) | TGRS Research Map | TGRS