Study on MTHFR (C677T & A1298C) Gene Polymorphisms in the Condition of Glucose Intolerance During Pregnancy

The study reveals that elevated platelet count and polymorphs increase the risk of developing GDM in pregnant women. Gestational age also plays a role. The study also finds a link between the MTHFR C677T SNP and the MTHFR A1298C gene polymorphism and the risk of gestational diabetes in Andhra Pradesh. This gives us new information about genetic and hematological factors.

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Publication Details

Journal
American Journal of Reproductive Immunology
Published
2025-05-01
DOI
https://doi.org/10.1111/aji.70081
Primary Topic
Gestational Diabetes Research and Management
Type
article
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article

Study on MTHFR (C677T & A1298C) Gene Polymorphisms in the Condition of Glucose Intolerance During Pregnancy

Nagarjuna Sivaraj, D. Lakshmi Lalitha, Sadia Roshan, Vijaya Sirisha Balaga et al.
American Journal of Reproductive Immunology
Gestational Diabetes Research and Management
article

Study on MTHFR (C677T & A1298C) Gene Polymorphisms in the Condition of Glucose Intolerance During Pregnancy

Nagarjuna Sivaraj, D. Lakshmi Lalitha, Sadia Roshan, Vijaya Sirisha Balaga, L. V. Simhachalam Kutikuppala, Bunga Papa Kusuma, Golla Varshitha, Arun Kumar Rao Panchanani, K. Kavya
article en

Abstract

The study reveals that elevated platelet count and polymorphs increase the risk of developing GDM in pregnant women. Gestational age also plays a role. The study also finds a link between the MTHFR C677T SNP and the MTHFR A1298C gene polymorphism and the risk of gestational diabetes in Andhra Pradesh. This gives us new information about genetic and hematological factors.

American Journal of Reproductive ImmunologyVol. 93(5)
Dr. NTR University of Health Sciences (IN)
Good health and well-being
Openalex Percentile: Top 87%
Gestational Diabetes Research and Management
DOISourceOpenAlex
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Study on MTHFR (C677T & A1298C) Gene Polymorphisms in the Condition of Glucose Intolerance During Pregnancy — Nagarjuna Sivaraj, D. Lakshmi Lalitha, et al. · American Journal of Reproductive Immunology (2025) | TGRS Research Map | TGRS