Prognostic Ability of the Indication for Adjuvant Systemic Therapy Based on Preoperative Biopsy and the Surgical Excision Specimen in Cases of Small Breast Tumors (CONSCIENCE): A Retrospective Cohort Study
Our study demonstrates disagreement between preoperative and postoperative assessment of malignancy grade and tumor size in approximately one fifth of the patients. Absence of postoperative information of primary tumor characteristics would have led erroneously to omission of adjuvant chemotherapy in less than 5% of the patients.
Authors
- Cornelis Verhoef (ORCID: https://orcid.org/0000-0001-9980-8613)
- Gerson M. Struik (ORCID: https://orcid.org/0000-0001-6886-4479)
- Erwin Birnie (ORCID: https://orcid.org/0000-0002-4534-4857)
- Thijs van Dalen (ORCID: https://orcid.org/0000-0003-0882-9086)
- Sophie M Wooldrik (ORCID: https://orcid.org/0009-0008-7293-5688)
- Suzanne Wilhelmus (ORCID: https://orcid.org/0000-0002-7794-5315)
- T.M.A.L. Klem
Institutions
- Sint Franciscus Gasthuis (NL)
- Erasmus MC Cancer Institute (NL)
Publication Details
- Journal
- Clinical Breast Cancer
- Published
- 2025-05-03
- DOI
- https://doi.org/10.1016/j.clbc.2025.04.018
- Citations
- 2
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.87