Acute myeloid leukemia presenting as an isolated orbital mass in an adult
In adults, MS presents rarely as an isolated finding in the orbit. Biopsy is indicated when an orbital mass recurs or does not fully respond to anti-inflammatory treatment. Establishing a diagnosis of MS can be a histopathological challenge. Genetic testing to evaluate for CEBPA mutations in the bZIP domain can predict a good prognosis.<sup>3,4</sup> When diagnosed, MS warrants referral to an oncologist for systemic evaluation and treatment due to its implication of AML.
Authors
- Joshua Menke (ORCID: https://orcid.org/0000-0002-4499-1104)
- Cindy S. Zhao (ORCID: https://orcid.org/0000-0001-9925-2985)
- Natalie Homer (ORCID: https://orcid.org/0000-0003-1671-4377)
- Lin Wang
Institutions
- Smith-Kettlewell Eye Research Institute (US)
- Stanford University (US)
Publication Details
- Journal
- American Journal of Ophthalmology Case Reports
- Published
- 2025-05-03
- DOI
- https://doi.org/10.1016/j.ajoc.2025.102350
- Citations
- 2
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 3.54