MG53 deficiency mediated skeletal muscle dysfunction in chronic obstructive pulmonary disease via impairing mitochondrial fission
Mitsugumin 53 is a vital regulator of sarcopenia in patients with chronic obstructive pulmonary disease. Thus, mitsugumin 53 and mitochondrial fission may be promising therapeutic targets for muscle dysfunction in chronic obstructive pulmonary disease.
Authors
- Ruixia Li (ORCID: https://orcid.org/0000-0002-0179-1807)
- Mingming Deng (ORCID: https://orcid.org/0000-0001-9454-7645)
- Jiaye Li (ORCID: https://orcid.org/0000-0002-5071-5325)
- Ziwen Zheng (ORCID: https://orcid.org/0000-0003-1711-6328)
- Yiding Bian (ORCID: https://orcid.org/0000-0003-1558-3918)
- Xiaoming Zhou (ORCID: https://orcid.org/0000-0002-6165-9277)
- Jinrui Miao (ORCID: https://orcid.org/0009-0004-5243-9194)
- Gang Hou (ORCID: https://orcid.org/0000-0003-3438-1764)
- Qin Zhang (ORCID: https://orcid.org/0009-0009-5451-4051)
- Weidong Xu (ORCID: https://orcid.org/0000-0001-6477-9461)
- Zilin Wang (ORCID: https://orcid.org/0000-0002-9598-3331)
- Yan Yin (ORCID: https://orcid.org/0000-0002-7266-3554)
- Chang Li
- Liwei Liao (ORCID: https://orcid.org/0000-0003-0152-8440)
- Kai Wang (ORCID: https://orcid.org/0009-0004-6559-2585)
Institutions
- Harbin Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China-Japan Friendship Hospital (CN)
- First Hospital of China Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Redox Biology
- Published
- 2025-05-03
- DOI
- https://doi.org/10.1016/j.redox.2025.103663
- Citations
- 5
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 5.82