Elevated Contact Stresses Compromise Activity-Mediated Cartilage Rehydration but not Lubrication
These results show that obesity is likely to directly physically impair articular cartilage function, and that obesity-driven tissue compression/strain, and not friction per se, may be the primary mechanical driver of cartilage dysfunction and OA risk.
Authors
- David L. Burris (ORCID: https://orcid.org/0000-0003-2687-7540)
- Christopher Price (ORCID: https://orcid.org/0000-0001-6573-6551)
- Meghan E. Kupratis
- Arnab Bhattacharjee (ORCID: https://orcid.org/0000-0002-9613-7911)
- Jamie Benson (ORCID: https://orcid.org/0000-0002-0709-4711)
- Shamimur Rahman Akanda (ORCID: https://orcid.org/0009-0000-9419-6662)
Institutions
- University of Delaware (US)
Publication Details
- Journal
- Annals of Biomedical Engineering
- Published
- 2025-05-03
- DOI
- https://doi.org/10.1007/s10439-025-03708-z
- Citations
- 2
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.67
Funders
- National Science Foundation
- Division of Civil, Mechanical and Manufacturing Innovation