Neurological disorders caused by recreational use of nitrous oxide—a retrospective study from a German metropolitan area and review of the literature
Our study confirms that the increasing incidence of N<sub>2</sub>O-induced neurotoxicity reported in other countries can also be observed in Germany. Therefore, it underlines the relevance of the current debate on health policies. In addition, our study highlights the pitfalls of vitamin B12 laboratory testing and emphasizes the need to address substance addiction in treatment.
Authors
- Christian Grefkes (ORCID: https://orcid.org/0000-0002-1656-720X)
- Marcel Hildner
- Asya Tshagharyan
- Pia S. Zeiner (ORCID: https://orcid.org/0000-0001-6626-9211)
- Iris Divé (ORCID: https://orcid.org/0000-0003-1096-5626)
- Elke Hattingen (ORCID: https://orcid.org/0000-0002-8392-9004)
- Joachim P. Steinbach (ORCID: https://orcid.org/0000-0002-4695-2483)
- Se-Jong You
Institutions
- Goethe University Frankfurt (DE)
- University Hospital Frankfurt (DE)
Publication Details
- Journal
- Neurological Research and Practice
- Published
- 2025-05-03
- DOI
- https://doi.org/10.1186/s42466-025-00385-0
- Citations
- 4
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 6.67