Based on the IL-33/ST2-MyD88 signaling pathway to explore the mechanism of aerobic exercise in antagonizing the inflammatory response in depressive mice

Aerobic exercise may counteract the CUMS depression model in mice by regulating the IL-33/ST2-MyD88 signaling pathway. The strong correlation of inflammatory cytokines between blood and hippocampus indicated that assessing inflammatory damage in the hippocampus could be done through blood tests of the signaling pathway and related cytokine levels.

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Publication Details

Journal
Cytokine
Published
2025-05-03
DOI
https://doi.org/10.1016/j.cyto.2025.156956
Primary Topic
IL-33, ST2, and ILC Pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

Based on the IL-33/ST2-MyD88 signaling pathway to explore the mechanism of aerobic exercise in antagonizing the inflammatory response in depressive mice

Ruilian Liu, Yilin Chen, He Qu, Qingyun Bai et al.
Cytokine
IL-33, ST2, and ILC Pathways
article

Based on the IL-33/ST2-MyD88 signaling pathway to explore the mechanism of aerobic exercise in antagonizing the inflammatory response in depressive mice

Ruilian Liu, Yilin Chen, He Qu, Qingyun Bai, Lei Gao
article en

Abstract

Aerobic exercise may counteract the CUMS depression model in mice by regulating the IL-33/ST2-MyD88 signaling pathway. The strong correlation of inflammatory cytokines between blood and hippocampus indicated that assessing inflammatory damage in the hippocampus could be done through blood tests of the signaling pathway and related cytokine levels.

CytokineVol. 191
Yichun University (CN), First Affiliated Hospital of Jiangxi Medical College (CN), Nanchang Normal University (CN), Jiangxi Normal University (CN)
Good health and well-being
Openalex Percentile: Top 89%
IL-33, ST2, and ILC Pathways
DOIOpen Access PDFOpenAlex
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Based on the IL-33/ST2-MyD88 signaling pathway to explore the mechanism of aerobic exercise in antagonizing the inflammatory response in depressive mice — Ruilian Liu, Yilin Chen, et al. · Cytokine (2025) | TGRS Research Map | TGRS