An Unusual Presentation of Fentanyl-Induced Rhabdomyolysis

Rhabdomyolysis is a pathological condition characterized by the breakdown of muscle tissue, which often presents with nonspecific imaging findings but necessitates prompt intervention. Providing a differential diagnosis based on imaging findings can significantly aid managing physicians, while a clear clinical context enhances the radiologist's ability to identify critical findings. In this report, we present a case of proximal lower extremity fentanyl-induced rhabdomyolysis identified on computed tomography (CT) angiography (CTA) performed to evaluate for compartment syndrome in the distal left lower extremity. We will discuss the expected imaging findings associated with rhabdomyolysis on both CT and magnetic resonance imaging (MRI).