Transmission pathways of Campylobacter jejuni between humans and livestock in rural Ethiopia are highly complex and interdependent
The transmission pathways of C. jejuni in our study area are highly complex and interdependent. While chickens are the most important reservoir of C. jejuni, ruminant reservoirs also contribute to the infections. The currently nonculturable species Candidatus C. infans is also highly prevalent in infants and is likely anthroponotic. Efforts to reduce the colonization of infants with Campylobacter and ultimately stunting in low-resource settings are best aimed at protecting proximate sources such as caretakers' hands, food and indoor soil through tight integration of the currently siloed domains of nutrition, food safety and water, sanitation and hygiene.
Authors
- Gireesh Rajashekara (ORCID: https://orcid.org/0000-0003-2443-6733)
- Sarah McKune (ORCID: https://orcid.org/0000-0002-3646-5921)
- Helen Smith (ORCID: https://orcid.org/0000-0002-4243-809X)
- Cecilie Thystrup (ORCID: https://orcid.org/0009-0007-8566-6491)
- Arie H. Havelaar (ORCID: https://orcid.org/0000-0002-6456-5460)
- Bahar Mummed (ORCID: https://orcid.org/0000-0003-0297-6616)
- Nigel French (ORCID: https://orcid.org/0000-0002-6334-0657)
- Nitya Singh (ORCID: https://orcid.org/0000-0003-1090-3046)
- Tine Hald (ORCID: https://orcid.org/0000-0002-1115-9792)
- Jonathan C. Marshall (ORCID: https://orcid.org/0000-0003-0758-9658)
- Mark Manary (ORCID: https://orcid.org/0000-0003-2733-9568)
- Menuka Bhandari (ORCID: https://orcid.org/0009-0004-0630-0837)
- Jemal Yusuf Hassen
Institutions
- Haramaya University (ET)
- University of Illinois Urbana-Champaign (US)
- Washington University in St. Louis (US)
- University of Florida (US)
- Virginia–Maryland College of Veterinary Medicine (US)
- Massey University (NZ)
- Virginia Tech (US)
- Technical University of Denmark (DK)
Publication Details
- Journal
- Gut Pathogens
- Published
- 2025-05-03
- DOI
- https://doi.org/10.1186/s13099-025-00691-7
- Citations
- 1
- Primary Topic
- Salmonella and Campylobacter epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- U.S. Department of Health and Human Services
- United States Agency for International Development
- Bill and Melinda Gates Foundation
- Minnesota Department of Health
- Colorado State University
- Wellcome Trust
- Rhode Island Department of Health
- University of Oxford