Cellulite – Etiology, Epidemiology and Management

Cellulite is a common dermatologic condition affecting 80-90% of post-pubertal females, particularly on the thighs, buttocks, and hips. It is characterized by dimpling and a "mattress-like" skin appearance, significantly impacting body image and quality of life. More prevalent in Caucasian women, it results from multifactorial causes, including hormonal influences (e.g., estrogen), structural differences in subcutaneous tissues, vascular changes, and low-grade inflammation. Lifestyle and aging further contribute to its severity. Treatments range from topical applications and energy-based devices to minimally invasive procedures, though results are often temporary. Due to its complex etiopathogenesis and structural changes, cellulite remains challenging to treat, necessitating realistic patient expectations and further research for improved and lasting solutions.

Authors

Publication Details

Journal
Review of Clinical Pharmacology and Pharmacokinetics - International Edition
Published
2025-05-03
DOI
https://doi.org/10.61873/vhxh4395
Primary Topic
Body Contouring and Surgery
Type
article
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article

Cellulite – Etiology, Epidemiology and Management

Εleni Sfyri
Review of Clinical Pharmacology and Pharmacokinetics - International Edition
Body Contouring and Surgery
article

Cellulite – Etiology, Epidemiology and Management

Εleni Sfyri
article en

Abstract

Cellulite is a common dermatologic condition affecting 80-90% of post-pubertal females, particularly on the thighs, buttocks, and hips. It is characterized by dimpling and a "mattress-like" skin appearance, significantly impacting body image and quality of life. More prevalent in Caucasian women, it results from multifactorial causes, including hormonal influences (e.g., estrogen), structural differences in subcutaneous tissues, vascular changes, and low-grade inflammation. Lifestyle and aging further contribute to its severity. Treatments range from topical applications and energy-based devices to minimally invasive procedures, though results are often temporary. Due to its complex etiopathogenesis and structural changes, cellulite remains challenging to treat, necessitating realistic patient expectations and further research for improved and lasting solutions.

Review of Clinical Pharmacology and Pharmacokinetics - International EditionVol. 39(Sup1)
Openalex Percentile: Top 83%
Body Contouring and Surgery
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