Induction of Fetal Hydrocephalus Followed by Ventriculoamniotic Shunting and End of Study Analysis in the Pregnant Sheep Model

The purpose of this manuscript was to document step-by-step instructions for hydrocephalus induction, shunt placement, and end of study analysis so that those who wish to develop a fetal hydrocephalus model, repeat our experience with ventriculoamniotic shunting, or test other interventions may benefit from our experience. Moreover, standardization of methodology will allow for meaningful comparisons between investigators.