Solute transport from synovial fluid to articular cartilage and subchondral bone at different stages of osteoarthritis in a live mouse model
The findings of this study advance the understanding of osteoarthritis pathogenesis by elucidating the role of solute transport alterations in cartilage and subchondral bone, thereby suggesting potential therapeutic targets aimed at modulating cartilage permeability to improve joint health in osteoarthritis.
Authors
- Bin Wang (ORCID: https://orcid.org/0000-0002-5396-6111)
- Mingshu Cui
- Mengcun Chen (ORCID: https://orcid.org/0000-0001-7986-5979)
- Yanmei Yang
Institutions
- Thomas Jefferson University (US)
Publication Details
- Journal
- Journal of Orthopaedic Translation
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.jot.2025.04.012
- Citations
- 3
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 5.00
Funders
- Rheumatology Research Foundation
- National Institutes of Health