Children with Acute Respiratory Distress Syndrome and Refractory Pneumonia Caused by Mycoplasma pneumoniae.

Refractory Mycoplasma pneumoniae pneumonia (RMPP) has been reported to be a common cause of bronchial malformations, shortness of breath, and dyspnea in children in recent years. With improvement in diagnosis and treatment, the incidence of RMPP is increasing. It has been reported that some patients develop resistance to macrolide antibiotics, in which the mechanism of action is complex and the treatment is harsh. Two children with RMPP underwent rapid progression 1 week after onset to acute respiratory distress syndrome. Ventilator-assisted ventilation was initiated and fiberoptic bronchoscopy was performed to assist in diagnosis and treatment. The treatment regimens were adjusted according to the rapid changes in status. The two children were cured and discharged from the hospital in stable condition.