Avian Influenza A(H5N1) Isolated from Dairy Farm Worker, Michigan
Influenza A(H5N1) viruses have been detected in US dairy cow herds since 2024. We assessed the pathogenesis, transmission, and airborne release of A/Michigan/90/2024, an H5N1 isolate from a dairy farm worker in Michigan, in the ferret model. Results show this virus caused airborne transmission with moderate pathogenicity, including limited extrapulmonary spread, without lethality.
Authors
- Troy J. Kieran (ORCID: https://orcid.org/0000-0002-3711-0727)
- Juan A. De La Cruz (ORCID: https://orcid.org/0000-0002-0712-065X)
- Claudia Pappas
- Xiangjie Sun (ORCID: https://orcid.org/0000-0002-9872-1337)
- Hui Zeng (ORCID: https://orcid.org/0000-0002-7456-6061)
- Yasuko Hatta (ORCID: https://orcid.org/0009-0000-1024-3792)
- Jessica A. Belser (ORCID: https://orcid.org/0000-0002-0755-7368)
- C. Todd Davis (ORCID: https://orcid.org/0000-0002-1429-974X)
- Taronna R. Maines (ORCID: https://orcid.org/0000-0002-4097-6724)
- Terrence M. Tumpey
- Joanna A. Pulit-Penaloza (ORCID: https://orcid.org/0000-0002-2187-5872)
- Nicole Brock
- Han Di (ORCID: https://orcid.org/0009-0008-0672-1497)
Publication Details
- Journal
- Emerging infectious diseases
- Published
- 2025-05-06
- DOI
- https://doi.org/10.3201/eid3106.250386
- Citations
- 12
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 16.25