Hepcidin and fungal infections: The liver fights back
Arekar et al. demonstrate that the liver peptide hepcidin holds therapeutic promises for treating invasive fungal infections by Candida albicans.<sup>1</sup> A hepcidin agonist improves infection outcome because it protects from renal pathology by diminishing iron bioavailability in kidneys.
Authors
- Karl Kuchler (ORCID: https://orcid.org/0000-0003-2719-5955)
Institutions
- Max Perutz Labs (AT)
Publication Details
- Journal
- Cell Reports
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.celrep.2025.115653
- Primary Topic
- Iron Metabolism and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Austrian Science Fund