Treatment with trypLE before freezing improves thawing integrity and functionality of sheep ovarian tissue
our findings suggest that trypLE pretreatment could provide a beneficial approach for maintaining the functions and viability of cryopreserved ovaries after thawing. Further research is needed to fully understand their impact and optimize cryopreservation protocols in this important clinical context.
Authors
- Ana Rosa Remacha (ORCID: https://orcid.org/0000-0002-1075-8267)
- María Royo‐Cañas (ORCID: https://orcid.org/0000-0003-4915-4839)
- Clara Malo (ORCID: https://orcid.org/0000-0003-2835-4823)
- Jesús Ciriza (ORCID: https://orcid.org/0000-0002-8666-622X)
- Alicia Marco
- Marta Gargallo
- Alejandro Ibáñez-Deler
- María Fons-Contreras
Institutions
- Universidad de Zaragoza (ES)
- Servicio Aragonés de Salud (ES)
- Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (ES)
- Instituto Ramón y Cajal de Investigación Sanitaria (ES)
- Instituto de Investigación Sanitaria Aragón (ES)
- Instituto Tecnológico de Aragón (ES)
- Instituto Aragonés de Ciencias de la Salud (ES)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-05-03
- DOI
- https://doi.org/10.1186/s13048-025-01593-7
- Citations
- 1
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Universidad de Zaragoza