Conditioning Electrical Stimulation Fails to Enhance Sympathetic Axon Regeneration

We conclude sympathetic axons may retain some regenerative ability, but no enhancement is exhibited after CES, which may be accounted for by the inability of the ES paradigm to recruit the small-caliber sympathetic axons into activity. Further studies will be needed to optimize ES parameters to enhance the regeneration of all neuron types.

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Publication Details

Journal
Neurorehabilitation and neural repair
Published
2025-05-02
DOI
https://doi.org/10.1177/15459683251335321
Citations
1
Primary Topic
Nerve injury and regeneration
Type
article
Field-Weighted Citation Impact
0.91

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article

Conditioning Electrical Stimulation Fails to Enhance Sympathetic Axon Regeneration

Alan G. Harris, Patricia J. Ward, Kevin Patel, Jordan N. Owyoung et al.
1 citations
Neurorehabilitation and neural repair
Nerve injury and regeneration
0.91
article

Conditioning Electrical Stimulation Fails to Enhance Sympathetic Axon Regeneration

Alan G. Harris, Patricia J. Ward, Kevin Patel, Jordan N. Owyoung, Tina Tian, HaoMin SiMa, David Kim
article en
1 citations

Abstract

We conclude sympathetic axons may retain some regenerative ability, but no enhancement is exhibited after CES, which may be accounted for by the inability of the ES paradigm to recruit the small-caliber sympathetic axons into activity. Further studies will be needed to optimize ES parameters to enhance the regeneration of all neuron types.

Neurorehabilitation and neural repairVol. 39(7)
Emory University (US)
National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke
Good health and well-being
Openalex Percentile: Top 28%
Nerve injury and regeneration
0.91
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