Role of <scp>LncRNA UCA1</scp> in <scp>OSCC CAFs</scp> : <scp>PD</scp> ‐ <scp>L1</scp> Upregulation and Tumor Progression

LncUCA1 upregulation in CAFs drives PD-L1 expression, inhibits CD8<sup>+</sup> T cell proliferation, and promotes immunosuppression. High LncUCA1 CAFs also enhance OSCC proliferation, migration, and invasion.

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Publication Details

Journal
Journal of Oral Pathology and Medicine
Published
2025-05-01
DOI
https://doi.org/10.1111/jop.13631
Citations
1
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
0.94

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article

Role of LncRNA UCA1 in OSCC CAFs : PD ‐ L1 Upregulation and Tumor Progression

Mengxiang Zhao, Xingxing Zhao, Liang Ding, Yanhong Ni et al.
1 citations
Journal of Oral Pathology and Medicine
Cancer-related molecular mechanisms research
0.94
article

Role of LncRNA UCA1 in OSCC CAFs : PD ‐ L1 Upregulation and Tumor Progression

Mengxiang Zhao, Xingxing Zhao, Liang Ding, Yanhong Ni, Nisha Zhu, Antonio Celentano, Qingang Hu, Yong Fu, Sufeng Zhao
article en
1 citations

Abstract

LncUCA1 upregulation in CAFs drives PD-L1 expression, inhibits CD8<sup>+</sup> T cell proliferation, and promotes immunosuppression. High LncUCA1 CAFs also enhance OSCC proliferation, migration, and invasion.

Journal of Oral Pathology and MedicineVol. 54(6)
Ningbo University (CN), The University of Melbourne (AU), Nanjing University (CN)
National Natural Science Foundation of China, Government of Jiangsu Province, Natural Science Foundation of Jiangsu Province, Nanjing Medical Science and Technique Development Foundation
Openalex Percentile: Top 26%
Cancer-related molecular mechanisms research
0.94
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