Semiparametric Inference for Functional Survival Models

In recent years, there has been growing interest among researchers in modeling right-censored survival data with functional covariates.While existing functional methods primarily focus on the Cox model, its proportional hazards assumption can be challenging to verify and may be violated in practice.To address this issue, we extend the ordinary differential equation (ODE) framework for survival data to incorporate functional covariates and develop an inference procedure for both scalar and functional parameters.Specifically, we establish asymptotic normality and semiparametric efficiency for the scalar coefficient estimators, enabling a valid inference procedure.Additionally, we derive an asymptotic simultaneous confidence band for the functional parameter.Simulations are conducted to evaluate the finite sample performance of the proposed method.

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Publication Details

Journal
Statistica Sinica
Published
2025-05-02
DOI
https://doi.org/10.5705/ss.202024.0180
Primary Topic
Statistical Methods and Inference
Type
article
Field-Weighted Citation Impact
0.00

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article

Semiparametric Inference for Functional Survival Models

Hongyi Zhou, Ying Yang, Wenqing Su, Qixian Zhong
Statistica Sinica
Statistical Methods and Inference
article

Semiparametric Inference for Functional Survival Models

Hongyi Zhou, Ying Yang, Wenqing Su, Qixian Zhong
article en

Abstract

In recent years, there has been growing interest among researchers in modeling right-censored survival data with functional covariates.While existing functional methods primarily focus on the Cox model, its proportional hazards assumption can be challenging to verify and may be violated in practice.To address this issue, we extend the ordinary differential equation (ODE) framework for survival data to incorporate functional covariates and develop an inference procedure for both scalar and functional parameters.Specifically, we establish asymptotic normality and semiparametric efficiency for the scalar coefficient estimators, enabling a valid inference procedure.Additionally, we derive an asymptotic simultaneous confidence band for the functional parameter.Simulations are conducted to evaluate the finite sample performance of the proposed method.

Statistica Sinica
National Natural Science Foundation of China
Zero hunger
Openalex Percentile: Top 91%
Statistical Methods and Inference
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Semiparametric Inference for Functional Survival Models — Hongyi Zhou, Ying Yang, et al. · Statistica Sinica (2025) | TGRS Research Map | TGRS