Tight Junction Proteins and Blood-brain Barrier Integrity in Pediatric Obsessive-compulsive Disorder: A Study on Claudin-5, Claudin-12, Occludin, Tricellulin, and Angulin-1
Our findings indicate that claudin-5, claudin-12, occludin, and tricellulin levels differ between individuals with OCD and healthy controls. These results suggest that tight junction proteins may contribute to the etiopathogenesis of OCD. Further research is needed to better understand the relationship between OCD and tight junction proteins.
Authors
- Ahmet Osman Kılıç (ORCID: https://orcid.org/0000-0002-3451-6764)
- Necati Uzun (ORCID: https://orcid.org/0000-0003-3381-2331)
- İbrahim Kılınç (ORCID: https://orcid.org/0000-0002-7729-7557)
- Filiz Akın-Kınay (ORCID: https://orcid.org/0009-0009-6705-5739)
Institutions
- Necmettin Erbakan University (TR)
- Ordu University (TR)
Publication Details
- Journal
- Clinical Psychopharmacology and Neuroscience
- Published
- 2025-05-02
- DOI
- https://doi.org/10.9758/cpn.25.1293
- Citations
- 7
- Primary Topic
- Barrier Structure and Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.90
Funders
- Necmettin Erbakan Üniversitesi