Fewer injections, less pain: Successful cyanocobalamin desensitization

Vitamin B12 (cobalamin) is a water-soluble vitamin that is derived from animal products such as red meat, dairy, and eggs. Cobalamin deficiency can be frequently seen in people all around the world. Desensitization is a treatment option if drug hypersensitivity develops and treatment is necessary. But intramuscular applications may cause treatment difficulties in such patients. A patient who developed cyanocobalamin deficiency due to pernicious anemia was shared. First, this patient was treated with cyanocobalamin. After treatment drug-induced hypersensitivity reaction developed. Desensitization was applied to the patient. Successful desensitization scheme was shared. Desensitization is of great value, as there are very limited treatment optıons in the literature on this subject, and it brings about a different option.