Alleles of <i>CYP3A5</i> and their association with renal function in chronic kidney disease

This study highlights a high prevalence of <i>CYP3A5</i> polymorphisms in the northeastern Thai population. The association of the <i>CYP3A5*3</i> allele with renal function parameters underscores the need for further research into the mechanisms by which <i>CYP3A5</i> affects kidney function, which could inform personalized CKD management strategies.

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Publication Details

Journal
PeerJ
Published
2025-05-02
DOI
https://doi.org/10.7717/peerj.19424
Citations
1
Primary Topic
Pharmacogenetics and Drug Metabolism
Type
article
Field-Weighted Citation Impact
1.56

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Alleles of CYP3A5 and their association with renal function in chronic kidney disease

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Alleles of CYP3A5 and their association with renal function in chronic kidney disease

Ubon Cha’on, Worachart Lert-itthiporn, Kanokwan Nahok, Apinya Jusakul, Chanpen Sriphan, Nadthanicha Artkaew, Sirirat Anutrakulchai, Onnapa Kongphan
article en
1 citations

Abstract

This study highlights a high prevalence of <i>CYP3A5</i> polymorphisms in the northeastern Thai population. The association of the <i>CYP3A5*3</i> allele with renal function parameters underscores the need for further research into the mechanisms by which <i>CYP3A5</i> affects kidney function, which could inform personalized CKD management strategies.

PeerJVol. 13
Khon Kaen University (TH)
Khon Kaen University
Peace, Justice and strong institutions
Openalex Percentile: Top 20%
Pharmacogenetics and Drug Metabolism
1.56
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