Postoperative complications following salvage neck dissection after (chemo)radiotherapy for head and neck squamous cell carcinoma: which patients are at high risk?
Of all patients who underwent salvage ND, 41% still had residual neck disease while 52% developed G ≥ 2 and 18% G3 complications. Although OS was not worse in these patients, accurate detection of residual neck disease is essential to spare considerable number of patients from unnecessary salvage ND with its possible complications. Patients with lymph nodes larger than 3 cm, HPV-negative disease and those treated by (modified)radical ND were at high risk of G ≥ 2 complications.
Authors
- Michiel W. M. van den Brekel (ORCID: https://orcid.org/0000-0002-6338-6743)
- Luc H. E. Karssemakers (ORCID: https://orcid.org/0000-0002-0257-8709)
- Zeno A.R. Gouw (ORCID: https://orcid.org/0000-0001-6206-6839)
- Willem Hans Schreuder (ORCID: https://orcid.org/0000-0003-0944-4356)
- Emilia C. Owers (ORCID: https://orcid.org/0009-0008-5242-2340)
- Maarten L. Donswijk (ORCID: https://orcid.org/0000-0003-2028-9713)
- Laura A. Smit (ORCID: https://orcid.org/0000-0003-1325-4790)
- Arash Navran (ORCID: https://orcid.org/0000-0001-7006-7807)
- W. Martin C. Klop (ORCID: https://orcid.org/0000-0002-6333-971X)
- Jan Paul de Boer (ORCID: https://orcid.org/0000-0001-6218-6128)
- Abrahim Al‐Mamgani (ORCID: https://orcid.org/0000-0001-5240-6510)
Institutions
- The Netherlands Cancer Institute (NL)
- Oncode Institute (NL)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1186/s12885-025-14232-7
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00