Serum creatinine to cystatin C ratio as monitoring biomarker in Chinese adult spinal muscular atrophy: a prospective cohort study
Long-term use of nusinersen effectively improves motor function and quality of life in adult SMA patients, and CCR may be a better indicator to reflect changes in motor function during treatment compared to other blood biomarkers.
Authors
- Qianqian Wei (ORCID: https://orcid.org/0009-0005-0734-9576)
- Sihui Chen (ORCID: https://orcid.org/0000-0002-3667-3077)
- Jiajia Fu (ORCID: https://orcid.org/0009-0003-0436-3116)
- Qiong Wang (ORCID: https://orcid.org/0000-0003-2564-7778)
- Xueping Chen
- Huifang Shang
- Xiaohui Lai
- Ruwei Ou (ORCID: https://orcid.org/0000-0002-9971-6185)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Orphanet Journal of Rare Diseases
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1186/s13023-025-03730-3
- Citations
- 3
- Primary Topic
- Neurogenetic and Muscular Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 4.88
Funders
- Department of Science and Technology of Sichuan Province
- Sichuan Province Science and Technology Support Program