Biological Variation of Erythrocyte Total, Metal-Free, and Zinc Protoporphyrin IX in Patients with Erythropoietic Protoporphyria and Healthy Subjects: Implications for Clinical Interpretation and Monitoring
The EPP patients had different set points for metal-free protoporphyrin, but the CVP(i) was similar, supporting the use of the same treatment goals when monitoring. This study is the first to use Bayesian analysis to demonstrate that personal BV is similar in patients with stable, chronic disease and different set points.
Authors
- Aasne K. Aarsand (ORCID: https://orcid.org/0000-0003-4167-8398)
- Sverre Sandberg (ORCID: https://orcid.org/0000-0001-9521-5087)
- Paul Kjetel Soldal Lillemoen
- Pernille Kjeilen Fauskanger (ORCID: https://orcid.org/0009-0000-5306-8082)
Institutions
- Haukeland University Hospital (NO)
- Deaconess Hospital (US)
- University of Bergen (NO)
Publication Details
- Journal
- Clinical Chemistry
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1093/clinchem/hvaf055
- Primary Topic
- Porphyrin Metabolism and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00