Synthesis and crystal structure of 3-(2-{3-[2-(2-oxooxazolidin-3-yl)ethoxy]quinoxalin-2-yloxy}ethyl)oxazolidin-2-one

In the title compound, C<sub>18</sub>H<sub>20</sub>N<sub>4</sub>O<sub>6</sub>, one of the oxazolidine rings adopts a twisted conformation and the other is a shallow envelope. In the crystal, weak C-H⋯O hydrogen bonds and π-π stacking inter-actions help to consolidate a three-dimensional architecture. The Hirshfeld surface analysis of the crystal structure indicates that the most important contributions for the crystal packing are from H⋯H (48.4%) and H⋯O/O⋯H (29.1%) contacts.

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Journal
Acta Crystallographica Section E Crystallographic Communications
Published
2025-05-02
DOI
https://doi.org/10.1107/s2056989025003755
Primary Topic
Synthesis and Biological Evaluation
Type
article
Field-Weighted Citation Impact
0.00

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article

Synthesis and crystal structure of 3-(2-{3-[2-(2-oxooxazolidin-3-yl)ethoxy]quinoxalin-2-yloxy}ethyl)oxazolidin-2-one

Ahmed Mazzah, Lhoussaine El Ghayati, Olivier Blacque, Nour El Hoda Mustaphi et al.
Acta Crystallographica Section E Crystallographic Communications
Synthesis and Biological Evaluation
article

Synthesis and crystal structure of 3-(2-{3-[2-(2-oxooxazolidin-3-yl)ethoxy]quinoxalin-2-yloxy}ethyl)oxazolidin-2-one

Ahmed Mazzah, Lhoussaine El Ghayati, Olivier Blacque, Nour El Hoda Mustaphi, Tuncer Hökelek, Fatima Ezzahra Aboutofil, Nada Kheira Sebbar
article en

Abstract

In the title compound, C<sub>18</sub>H<sub>20</sub>N<sub>4</sub>O<sub>6</sub>, one of the oxazolidine rings adopts a twisted conformation and the other is a shallow envelope. In the crystal, weak C-H⋯O hydrogen bonds and π-π stacking inter-actions help to consolidate a three-dimensional architecture. The Hirshfeld surface analysis of the crystal structure indicates that the most important contributions for the crystal packing are from H⋯H (48.4%) and H⋯O/O⋯H (29.1%) contacts.

Acta Crystallographica Section E Crystallographic CommunicationsVol. 81(6)
Mohammed V University (MA), University of Zurich (CH), Université Ibn Zohr (MA), Hacettepe University (TR)
Hacettepe Üniversitesi
Sustainable cities and communities
Openalex Percentile: Top 93%
Synthesis and Biological Evaluation
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Synthesis and crystal structure of 3-(2-{3-[2-(2-oxooxazolidin-3-yl)ethoxy]quinoxalin-2-yloxy}ethyl)oxazolidin-2-one — Ahmed Mazzah, Lhoussaine El Ghayati, et al. · Acta Crystallographica Section E Crystallographic Communications (2025) | TGRS Research Map | TGRS