Young apple polyphenol extract prevents diabetic cognitive dysfunction by promoting TET2-mediated active DNA demethylation in the brain of diabetic mice
Consequently, YAPE effectively delays progression from diabetes to DCD by facilitating TET2-mediated active DNA demethylation.
Authors
- Qingxin Li (ORCID: https://orcid.org/0000-0001-7460-9546)
- Zhongshi Qi
- Hongzhuan Yu
- Yuntiao Chen
- Run Liu (ORCID: https://orcid.org/0000-0002-2578-7941)
- Xiaochen Zhang (ORCID: https://orcid.org/0009-0001-2230-9813)
- Jiacheng Fang
- Liying Zhou (ORCID: https://orcid.org/0000-0002-0620-6216)
Institutions
- Qingdao University (CN)
- Weifang Medical University (CN)
- Tangshan College (CN)
- Weifang Chinese Medicine Hospital (CN)
- The University of Adelaide (AU)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-05-02
- DOI
- https://doi.org/10.3389/fnut.2025.1580775
- Citations
- 3
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.49