Synthesis, target analysis, and cerebroprotective effects of novel imide antioxidants via the Nrf2/HO-1 pathway in cerebral ischemia-reperfusion injury
This study provides a new drug development strategy and candidate drug for the treatment of CIRI, offering ideas for the design of new antioxidants.
Authors
- Zhongkai Wu (ORCID: https://orcid.org/0000-0003-1184-1182)
- Xiping Wu (ORCID: https://orcid.org/0000-0002-0189-2050)
- Yinqi Chen (ORCID: https://orcid.org/0000-0002-6885-3478)
- Hua Zhou
- Zhoudi Liu
- Lili Huang (ORCID: https://orcid.org/0000-0003-3251-6004)
- Huihui Chen (ORCID: https://orcid.org/0000-0002-3905-7907)
- Zhiwei Zheng (ORCID: https://orcid.org/0009-0001-1330-5247)
Institutions
- Ningbo Medical Center Lihuili Hospital (CN)
- Shaoxing Second Hospital (CN)
- Shaoxing No.6 People's Hospital (CN)
- Zhejiang Provincial People's Hospital (CN)
- Shaoxing People's Hospital (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-05-02
- DOI
- https://doi.org/10.3389/fphar.2025.1552717
- Citations
- 1
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.81