CASPAR: a retrospective cohort study of the high-concentration capsaicin topical system in patients with painful diabetic peripheral neuropathy of the feet
This real-world study in patients with pDPN of the feet demonstrates that ongoing HCCTS treatments continue to improve pain intensity, mood, and QoL, while concomitant medication use decreases. Benefits from treatment were lost following HCCTS discontinuation. These findings emphasize the importance of ongoing treatments to achieve the potential of HCCTS in improving outcomes for patients with pDPN.
Authors
- Ζoltan Κender (ORCID: https://orcid.org/0000-0003-0745-1587)
- Mariëlle Eerdekens (ORCID: https://orcid.org/0000-0001-6198-4806)
- Tamara Quandel
- Lucía García‐Guerra (ORCID: https://orcid.org/0000-0002-8321-3137)
- Samuel D. Allen (ORCID: https://orcid.org/0000-0003-1482-1830)
- Rita Freitas
- Michael A. Überall
- Sylvia Engelen
- Tawfik Fajri
Institutions
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Morristown Medical Center (US)
- Grünenthal Group (Germany) (DE)
- Grunenthal (Spain) (ES)
- Deutsches Diabetes-Zentrum e.V. (DE)
- German Center for Diabetes Research (DE)
- Heinrich Heine University Düsseldorf (DE)
- Grünenthal Group (Germany) (DE)
Publication Details
- Journal
- BMJ Open Diabetes Research & Care
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1136/bmjdrc-2024-004864
- Citations
- 5
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.82