Role of Maternal Obesity in Offspring Cardiovascular Development and Congenital Heart Defects
These findings demonstrate that maternal obesity alone can result in cardiac defects through mechanisms similar to those associated with maternal hyperglycemia. This study provides valuable insight into the role of maternal obesity, a growing and modifiable risk factor, in the development of the most common birth defect, congenital heart disease.
Authors
- Weinian Shou (ORCID: https://orcid.org/0000-0001-5538-9605)
- Matthew D. Durbin (ORCID: https://orcid.org/0000-0002-1686-903X)
- Swetansu K. Hota (ORCID: https://orcid.org/0000-0003-3105-9729)
- Kok Lim Kua (ORCID: https://orcid.org/0000-0002-6351-4506)
- Laura S. Haneline
- James B. Zwierzynski (ORCID: https://orcid.org/0009-0005-7027-0916)
- Ashleigh McMullan
- Nina Jain
Institutions
- University School (US)
- Indiana University School of Medicine
- Indiana University (US)
- Stanford University (US)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1161/jaha.124.039684
- Citations
- 5
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 6.77
Funders
- March of Dimes Foundation
- American Heart Association
- Riley Children's Foundation
- National Institutes of Health
- School of Medicine, Indiana University
- National Cancer Institute
- National Center for Advancing Translational Sciences