The role of serum indoxyl sulfate and Klotho protein in cardiovascular complications among chronic kidney disease patients

In patients with chronic kidney disease (CKD), the incidence of cardiovascular complications is significantly higher than in the general population. The increase of serum IS level and the decrease of serum Klotho protein level are closely related to cardiac injury, it IS suggested that serum IS level and Klotho protein level may be a good index for monitoring cardiovascular injury in CKD patients.

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Publication Details

Journal
The International Journal of Artificial Organs
Published
2025-05-01
DOI
https://doi.org/10.1177/03913988251334878
Citations
2
Primary Topic
Cardiovascular Function and Risk Factors
Type
article
Field-Weighted Citation Impact
2.78
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article

The role of serum indoxyl sulfate and Klotho protein in cardiovascular complications among chronic kidney disease patients

Li Zhang, Beining Wang, Ye Li, Qiang Liu et al.
2 citations
The International Journal of Artificial Organs
Cardiovascular Function and Risk Factors
2.78
article

The role of serum indoxyl sulfate and Klotho protein in cardiovascular complications among chronic kidney disease patients

Li Zhang, Beining Wang, Ye Li, Qiang Liu, Weina Zhang, Si Zhang, Qian Wang, Tiantian Jin, Jie Liang, Yan Gao
article en
2 citations

Abstract

In patients with chronic kidney disease (CKD), the incidence of cardiovascular complications is significantly higher than in the general population. The increase of serum IS level and the decrease of serum Klotho protein level are closely related to cardiac injury, it IS suggested that serum IS level and Klotho protein level may be a good index for monitoring cardiovascular injury in CKD patients.

The International Journal of Artificial OrgansVol. 48(5)
Affiliated Hospital of Chengde Medical College (CN), Affiliated Hospital of Hebei University (CN), Hebei University (CN)
Good health and well-being
Openalex Percentile: Top 10%
Cardiovascular Function and Risk Factors
2.78
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