An in-depth exploration of the association between olanzapine, quetiapine and acute pancreatitis based on real-world datasets and network toxicology analysis
The pharmacovigilance analysis investigated the signal intensity, clinical features, risk factors, and onset time of AP associated with olanzapine and quetiapine. Network toxicology analysis suggested that the toxic effects of olanzapine and quetiapine may be related to their hub genes.
Authors
- Liying Song (ORCID: https://orcid.org/0000-0001-5689-7134)
- Jia Yao (ORCID: https://orcid.org/0000-0001-8724-577X)
- Shuang Wang (ORCID: https://orcid.org/0000-0002-8261-0018)
- Yuanjie Sun (ORCID: https://orcid.org/0009-0009-6682-1817)
- Haonan Zhou
Institutions
- Shanxi Medical University (CN)
- First Hospital of Shanxi Medical University (CN)
- Shanxi Academy of Medical Sciences (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-05-02
- DOI
- https://doi.org/10.3389/fphar.2025.1529416
- Citations
- 1
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- ShanXi Science and Technology Department